UPDATE 8.30pm: QUEENSLAND Police confirmed the Bruce Highway was reopened at 5.10pm after the badly damaged four-wheel-drive had been removed from the ditch.
It is still unknown whether the caravan had been recovered.
EARLIER: EMERGENCY services are responding to a crash north of Rockhampton which has blocked the Bruce Highway.
Queensland Police said the single vehicle crash which occurred around 3.30pm, 1km past Rosmoya Rd, near Plentiful Creed Rd, Yaamba.
A four-wheel-drive was towing a caravan which has rolled, causing the vehicle to catch on fire and fuel to be spilled on the road.
The highway is currently blocked and police are directing traffic.
Three Queensland Fire and Emergency Services crews are currently working to make the area safe and clean the fuel off the road.
Queensland Ambulance confirmed two patients were in transit to Rockhampton hospital, one as a precaution and the other experiencing shoulder pain.